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Maternal Health Resource Center

Understanding placental complications in pregnancy

Trusted, evidence-based resources for women navigating placenta previa, placenta accreta spectrum, and related maternal complications. Know your options, understand your risks, and connect with specialists.

Placenta Previa

What to expect after diagnosis

Understanding monitoring, activity restrictions, and delivery planning with your care team.

1 in 200
pregnancies affected by placenta previa
🩺

Specialist-reviewed content updated regularly

1 in 200
Placenta Previa prevalence
1 in 300–500
Placenta Accreta incidence
~90%
Low-lying placentas resolve by term
3x
Increase in accreta since the 1980s

Placental complications explained

Learn about the two primary placental complications, their symptoms, diagnosis methods, and management strategies recommended by maternal-fetal medicine specialists.

Placenta Previa

Placenta Previa

A condition where the placenta partially or completely covers the cervical opening (os). This can cause painless vaginal bleeding, particularly in the third trimester, and typically requires cesarean delivery.

Risk level:
Placenta Accreta Spectrum

Placenta Accreta Spectrum

A group of conditions (accreta, increta, percreta) where the placenta abnormally attaches too deeply into the uterine wall. Often associated with prior C-sections, it carries a higher risk of major hemorrhage.

Risk level:
Placenta Previa

Placenta previa often has no symptoms early on, but key warning signs include:

Painless vaginal bleeding — especially in 2nd or 3rd trimester

Bright red bleeding — can begin suddenly without warning

Uterine cramping — especially after bleeding episodes

Breech or transverse position — baby may not be head-down

Recurring bleeding — episodes may stop and restart

Large uterus for gestational age — less common indicator

Note: Some women have no bleeding at all. Previa is often diagnosed via routine ultrasound.

Placenta previa is diagnosed using imaging. The standard diagnostic pathway involves:

Transvaginal ultrasound — most accurate method for placental localization

Transabdominal ultrasound — often used first; may miss low-lying placenta

MRI — used when ultrasound is inconclusive or accreta is suspected

Follow-up scans at 32–36 weeks — ~90% of low-lying placentas resolve by term

Management depends on gestational age, symptoms, and degree of previa:

Pelvic rest — no intercourse, tampons, or pelvic exams

Activity restriction — reduced physical exertion; sometimes bed rest

Regular monitoring — ultrasound every 2–4 weeks in 3rd trimester

Corticosteroids — if preterm delivery is anticipated to mature fetal lungs

Hospitalization — for heavy bleeding or if far from medical care

Planned cesarean — typically at 36–37 weeks; earlier if bleeding persists

Placenta Accreta Spectrum

Placenta accreta spectrum (PAS) is often asymptomatic during pregnancy. Risk factors and signs include:

Prior cesarean delivery — #1 risk factor; risk increases with each C-section

Prior uterine surgery — myomectomy, D&C, endometrial ablation, or any procedure that scars the uterine wall

Low-lying or previa placenta — PAS very common when previa overlies a uterine scar

IVF / frozen embryo transfer — research shows significantly elevated PAS risk, especially with hormone replacement cycles

Abnormal 3rd trimester bleeding — may indicate partial abruption

Difficulty with placental delivery — often first recognized at time of birth

Elevated AFP — abnormal maternal serum screening result may prompt further workup

PAS is often not detected until delivery. When suspected, diagnosis involves:

Transvaginal ultrasound — first-line imaging; looks for loss of clear zone, lacunae (irregular vascular spaces), and abnormal placental blood flow

Color Doppler ultrasound — identifies abnormal vascularity and uterine wall invasion

MRI — used when ultrasound is inconclusive; helps assess depth of invasion and involvement of bladder or surrounding organs

Elevated maternal AFP — abnormal second-trimester serum screening may prompt further imaging workup

History review — prior C-sections, uterine surgeries, IVF, and placenta location are key diagnostic factors

Referral to MFM specialist — formal diagnosis and delivery planning should involve a maternal-fetal medicine specialist at a PAS center

Note: PAS in IVF patients is significantly less likely to be detected prenatally — proactive screening is essential even without classic risk factors.

PAS requires a highly specialized, multidisciplinary approach. Management typically involves:

Delivery at a PAS Center of Excellence — hospitals with dedicated multidisciplinary teams

MFM + surgical specialists — OB, urology, vascular surgery, and interventional radiology

Cell salvage and transfusion readiness — large blood loss is expected

Planned hysterectomy — typically recommended to prevent life-threatening hemorrhage

Delivery at 34–36 weeks — planned preterm birth reduces emergency risk

Counseling on fertility — hysterectomy ends future pregnancies; discussion is essential

The placenta accreta spectrum describes three grades of abnormal placental attachment, defined by how deeply the placenta invades the uterine wall:

Endometrium Myometrium Placenta surface attachment only
Grade 1 — Accreta

Placenta Accreta

Attaches too firmly to the uterine wall but does not penetrate the muscle. The normal separating tissue (decidua) is absent.

~75% of all PAS cases
Endometrium Myometrium Placenta roots into muscle layer
Grade 2 — Increta

Placenta Increta

Invades into the myometrium (uterine muscle). Separation at delivery is extremely difficult and hemorrhage risk is significantly elevated.

~15% of all PAS cases
Endometrium Myometrium Placenta bladder
Grade 3 — Percreta

Placenta Percreta

The most severe form — penetrates entirely through the uterine wall and may invade surrounding organs such as the bladder or bowel.

~5–10% of all PAS cases

Note: All three types require delivery at a PAS Center of Excellence. Depth of invasion determines surgical complexity and blood loss risk.

Frequently asked questions

Yes — in many cases, particularly when diagnosed early in the second trimester. As the uterus grows, the placenta can appear to "migrate" upward and away from the cervix. Studies suggest that the majority of low-lying placentas identified at the 20-week anatomy scan will resolve by 36 weeks. However, a complete previa detected late in pregnancy is far less likely to resolve and usually requires cesarean delivery. Follow-up ultrasounds at 32–36 weeks are standard to assess whether resolution has occurred.
These three terms describe increasing depths of abnormal placental attachment. In placenta accreta, the placenta attaches too firmly to the uterine wall but does not penetrate the muscle layer. In placenta increta, the placenta grows into the uterine muscle. In placenta percreta — the most severe form — the placenta penetrates entirely through the uterine wall and may attach to adjacent organs such as the bladder or bowel. Together, these are called the Placenta Accreta Spectrum (PAS).
Yes. Uterine scarring from prior cesarean delivery significantly increases the risk of both placenta previa and placenta accreta spectrum in future pregnancies. The risk is cumulative — with one prior C-section, the PAS risk is approximately 0.3%; with two it rises to around 0.6%; with three or more the risk can exceed 2%. Other uterine surgeries — including myomectomy, D&C, and endometrial ablation — also create scar tissue that raises PAS risk, even without a prior C-section. When a low-lying placenta is found in women with any uterine surgical history, MFM evaluation and MRI are typically recommended.
Yes — research increasingly shows that IVF pregnancies, particularly those using frozen embryo transfer (FET) in a hormone replacement cycle, carry a significantly elevated risk of placenta accreta spectrum. One large study found that women who underwent IVF had more than 5 times the risk of PAS compared to non-IVF pregnancies. Importantly, PAS in IVF patients is also less likely to be detected before delivery — because these women often lack the traditional risk factors (prior C-sections, placenta previa) that prompt clinicians to screen. If you conceived via IVF, particularly through frozen embryo transfer, speak with your OB or MFM about targeted PAS screening even if you have no prior uterine scars.
For complete or major placenta previa, vaginal delivery is not safe and cesarean section is required. For a low-lying placenta where the edge is within 2 cm of the cervical os, vaginal delivery may sometimes be possible under close monitoring, but this depends on individual circumstances and should be thoroughly discussed with your MFM specialist. A marginal previa at the edge of the os is typically still managed with cesarean delivery at most institutions.
A PAS Center of Excellence is a hospital that has a dedicated multidisciplinary team experienced in managing placenta accreta spectrum deliveries. These centers have protocols in place for high blood loss, including cell salvage, massive transfusion protocols, interventional radiology support, and surgical specialists. The Accreta Foundation and SMFM both advocate for women with PAS to deliver at such centers, as outcomes are significantly better compared to institutions without this specialized experience.
Key questions to consider: What type of previa or PAS do I have, and how confident are you in the diagnosis? Should I be referred to a Maternal-Fetal Medicine specialist? Will I need additional imaging (MRI)? What activity restrictions do I need to follow? Where should I deliver, and does that facility have a multidisciplinary PAS team? What are the warning signs I should watch for at home? When would you recommend early delivery, and will my baby need NICU support? If hysterectomy is a possibility, what are my options for discussing fertility preservation?

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When to seek emergency care immediately

If you have been diagnosed with placenta previa or are at risk for placenta accreta, go to the nearest emergency room immediately if you experience heavy vaginal bleeding, severe abdominal pain, a rapid drop in fetal movement, signs of shock (dizziness, rapid heartbeat, fainting), or any bleeding that soaks more than one pad per hour.

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Medical Disclaimer: The content on this website is for informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of your obstetrician, maternal-fetal medicine specialist, or other qualified health provider with any questions you may have regarding your pregnancy or medical condition. In an emergency, call 911 or go to the nearest emergency room immediately.